Current Lab Members
Aaron Atkinson, Ph.D.
Dartmouth College, post-doctoral fellow
I am investigating mechanisms by which yeast regulate the mitochondrial zinc pools.
Megan Bestwick
B.S. Southern Oregon University 2001
M.S. University of Washington
I am focused on protein interaction studies with Coa1, a new cytochrome oxidase assembly factor.
Paul Cobine, Ph.D.
University of Queensland; post-doctoral fellow
I am characterizing a pool of copper ions within the mitochondrial matrix that appears to be the source of Cu(I) used for the metallation of cytochrome c oxidase within the intermembrane space (IMS). I am attempting to identify the transporter responsible for moving Cu(I) from the matrix to the IMS. I will be leaving the Winge Lab this fall to take a position at Auburn University.
Greg Keller, B.S.
Univ. Illinois, Laboratory manager
I am studying the copper-metalloregulation of Mac1 and Ace1 focusing on the routing of Cu(I) to the nucleus for interaction with these two transcription factors. I am also studying iron sensing by Aft1 in yeast.
Hyung Kim, Ph.D.
University of Kansas
My research involves structural characterization of the mitochondrial matrix copper ligand complex.
Oleh Khalimonchuk, Ph.D.
University of Dresden Germany
I am working on the roles of Cox11, Shy1 and Pet191 in the assembly of cytochrome oxidase.
I am studying a series of assembly factors implicated in the maturation of cytochrome
oxidase in yeast. I am interested in understanding the function of these factors
in copper metallation of CcO within the IMS.
Pam Smith, B.S.
Viterbo University, 2003; graduate student
I am working on the structural identity of ligands stabilizing Zn and Fe ions in the mitochondrial matrix.
