Publications

These publications are downloadable using Adobe Acrobat Reader (versions 5.0 and higher) where the red “PDF” icon appears.  If you would like a hard copy reprint or if there are any problems with the links, please email Rachel Bookman.

Macbeth, M.R., Bass, B.L. (2007).  Large-scale overexpression and purification of ADARs from Saccharomyces cerevisiae for biophysical and biochemical studies.  In Methods in Enzymology, (ed. J.M. Gott) Elsevier Inc., 424: 319-331.

Welker, N.C., Habig, J.W., Bass, B.L. (2007).  Genes misregulated in C. elegans deficient inDicer, RDE-4, or RDE-1, are enriched for innate immunity genes. RNA, 13: 1090-1102. Supporting Material

Bass, B.L. (2007). How does RNA editing affect dsRNA-mediated gene silencing? Cold Spring Harbor Symposia on Quantitative Biology, 2006, 71: 285-292.

Habig, J.W., Dale, T., Bass, B.L. (2007). miRNA editing--we should have inosine this coming. Molecular Cell, 2007, 25: 792-793.

Parker, G.S., Eckert, D.M., Bass, B.L. (2006). RDE-4 preferentially binds long dsRNA and its dimerization is necessary for cleavage of dsRNA to siRNA. RNA, 12: 807-818. 

Bass, B.L., Hellwig, S., Hundley, H.A. (2005). A nuclear RNA is cut out for translation. Cell, 123: 181-193.

Macbeth, M.R., Schubert, H.L., VanDemark, A.P., Lingam, A.T., Hill, C.P., and Bass, B.L. (2005). Inositol hexakisphosphate is bound in the ADAR2 core and required for RNA editing. Science, 309: 1534-1539.    Supporting Material

Haudenschild, B.L., Maydanovych, O., Véliz, E.A., Macbeth, M.R., Bass, B.L. and Beal, P.A. (2004). A transition state analog for an RNA-editing reaction. J. Am. Chem. Soc., 126: 11213-9.   Supporting Material

Macbeth, M.R., Lingam, A.T. and Bass, B.L. (2004). Evidence for auto-inhibition by the N-terminus of hADAR2 and activation by dsRNA binding. RNA, 10: 1563-1571.

Tonkin, L.A. and Bass, B.L. (2003). Mutations in RNAi rescue aberrant chemotaxis of ADAR mutants. Science, 302: 1725.

Tonkin, L.A., Saccomanno, L., Morse, D. P., Brodigan, T., Krause, M. and Bass, B.L. (2002). RNA editing by ADARs is important for normal behavior in Caenorhabditis elegans. EMBO J., 21: 6025-6035.

Knight, S.W., Bass, B.L. (2002). The role of RNA editing by ADARs in RNAi. Molecular Cell, 10: 809-817.

Bass, B.L. (2002). RNA editing by adenosine deaminases that act on RNA. Annu. Rev. Biochem., 71: 817-846.

Morse, D.P., Aruscavage, P.J., Bass, B.L. (2002). RNA hairpins in noncoding regions of human brain and Caenorhabditis elegans mRNA are edited by adenosine deaminases that act on RNA. Proc. Natl. Acad. Sci. USA, 99: 7906-7911.

Knight, S.W. and Bass, B.L. (2001). A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in C. elegans. Science, 293: 2269-2271.

Bass, B.L. (2001). The short answer [news and views]. Nature, 411: 428-429.

Bass, B.L., Editor (2001). RNA Editing: Frontiers in Molecular Biology, Oxford University Press.

Hough, R.F. and Bass, B.L. (2001). Adenosine deaminases that act on RNA. In RNA Editing: Frontiers in Molecular Biology, (ed. B.L. Bass) Oxford University Press, pp. 77-108.

Lehmann, K.A. and Bass, B.L. (2000). Double-stranded RNA adenosine deaminases ADAR1 and ADAR2 have overlapping specificities. Biochemistry, 39: 12875-12884.

Domeier, M.E., Morse, D.P. Knight, S.W., Portereiko, M., Bass, B.L., and Mango, S.E. (2000). A link between RNA interference and nonsense-mediated decay in Caenorhabditis elegans. Science, 289: 1928-1930.

Bass, B.L. (2000). Double-stranded RNA as a template for gene silencing [minireview]. Cell, 101: 235-238.

Öhman, M., Källman, A.M., and Bass, B.L. (2000). In vitro analysis of the binding of ADAR2 to the pre-mRNA encoding the GluR-B R/G site. RNA, 6: 687-697.

Aruscavage, P.J. and Bass, B.L. (2000). A phylogenetic analysis reveals an unusual sequence conservation within introns involved in RNA editing. RNA, 6: 257-269.

Hough, R.F., Lingam, A.T. and Bass, B.L. (1999). Caenorhabditis elegans mRNAs that encode a protein similar to ADARs derive from an operon containing six genes. Nucleic Acids Res., 27: 3424-3432.

Lehmann, K.A. and Bass, B.L. (1999). The importance of internal loops within RNA substrates of ADAR1. J. Mol. Biol., 291: 1-14.

Morse, D.P. and Bass, B.L. (1999). Long RNA hairpins that contain inosine are present in Caenorhabditis elegans poly (A)+ RNA. Proc. Natl. Acad. Sci. USA, 96: 6048-6053.

Finerty, P.J., Jr., and Bass, B.L. (1999). Subsets of the zinc finger motifs in dsRBP-ZFa can bind double-stranded RNA. Biochemistry, 38: 4001-4007.

Saccomanno, L. and Bass, B.L. (1999). A minor fraction of basic fibroblast growth factor mRNA is deaminated in Xenopus stage VI and matured oocytes. RNA, 5: 39-48.

Bass, B.L., Öhman, M. (1999). RNA Editing. In Comprehensive Natural Products Chemistry, Vol. 6: Prebiotic Chemistry, Molecular Fossils, Nucleosides and RNA, (eds. D. Söll, S. Nishimura, and P. Moore) Elsevier Science Ltd., pp. 97-108.

Polson, A.G., Ley, H.L. III., Bass, B.L. and Casey, J.L. (1998). Hepatitis delta virus RNA editing is highly specific for the amber/W site and is suppressed by hepatitis delta antigen. Mol. Cell. Biol., 18: 1919-1926.

Paul, M.S. and Bass, B.L. (1998). Inosine exists in mRNA at tissue-specific levels and is most abundant in brain mRNA. EMBO J., 17: 1120-1127.

Morse, D.P. and Bass, B.L. (1997). Detection of inosine in messenger RNA by inosine-specific cleavage. Biochemistry, 36: 8429-8434.

Finerty, P.J., Jr. and Bass, B.L. (1997). A Xenopus zinc finger protein that specifically binds dsRNA and RNA-DNA hybrids. J. Mol. Biol., 271: 195-208.

Hough, R.F. and Bass, B.L. (1997). Analysis of Xenopus dsRNA adenosine deaminase cDNAs reveals similarities to DNA methyltransferases. RNA, 3: 356-370.

Bass, B.L., Nishikura, K., Keller, W., Seeburg, P.H., Emeson, R.B., O'Connell, M.A., Samuel, C.E., and Herbert, A. (1997). A standardized nomenclature for adenosine deaminases that act on RNA [letter to the editor]. RNA, 3: 947-949.

Bass, B.L. (1997). RNA editing and hypermutation by adenosine deamination. Trends Biochem. Sci., 22: 157-162.

Polson, A.G., Bass, B.L. and Casey, J.L. (1996). RNA editing of hepatitis delta virus antigenome by dsRNA adenosine deaminase. Nature, 380: 454-456.

Hurst, S.R., Hough, R.F., Aruscavage, P.J. and Bass, B.L. (1995). Deamination of mammalian glutamate receptor RNA by Xenopus dsRNA adenosine deaminase: similarities to in vivo RNA editing. RNA, 1: 1051-1060.

Bass, B.L. (1995). An I for editing. Current Biology, 5: 598-600.

Bass, B. L. (1995). Double-stranded RNA binding proteins and their substrates. Nucleic Acids Symposium Series, 33: 13-15.

Polson, A.G. and Bass, B.L. (1994). Preferential selection of adenosines for modification by double-stranded RNA adenosine deaminase. EMBO J., 13: 5701-5711.

Saccomanno, L. and Bass, B.L. (1994). The cytoplasm of Xenopus oocytes contains a factor that protects double-stranded RNA from adenosine-to-inosine modification. Mol. Cell. Biol., 14: 5425-5432.

Hough, R.F. and Bass, B.L. (1994). Purification of the Xenopus laevis double-stranded RNA adenosine deaminase. J. Biol. Chem., 269: 9933-9939.

Bass, B.L., Hurst, S.R. and Singer, J.D. (1994). Binding properties of newly identified Xenopus proteins containing dsRNA-binding motifs. Current Biology, 4: 301-314.

Bass, B.L. (1993). RNA editing: New uses for old players in the RNA world. In The RNA World, (eds. R. Gesteland and J. Atkins) Cold Spring Harbor Laboratory Press, pp. 383-418.

Bass, B.L. (1992). The dsRNA unwinding/modifying activity: fact and fiction. Seminars in Developmental Biology, 3: 425-433.

Bass, B.L. (1992). The double-stranded RNA unwinding/modifying activity. In Antisense RNA and DNA, (ed. J.A.H. Murray) Wiley-Liss, New York, pp. 159-174.

Polson, A.G., Crain, P.F., Pomerantz, S.C., McCloskey, J.A. and Bass, B.L. (1991). The mechanism of adenosine to inosine conversion by the double-stranded RNA unwinding/modifying activity: a high-performance liquid chromatography-mass spectrometry analysis. Biochemistry, 30: 11507-11514.