Inositol hexakisphosphate

double-stranded RNA

Mating C. elegans

Brenda L. Bass, Ph.D.

Research in my laboratory is focused on double-stranded RNA (dsRNA)--its biological functions and the proteins that bind it to mediate these functions. At present our studies are divided between two dsRNA-mediated pathways: RNA editing by adenosine deaminases that act on RNA (ADARs), and gene-silencing (e.g., RNA interference). We anticipate future studies in additional pathways since our work suggests long, cellular dsRNA has unrecognized functions in stress, immunity and aging.   More....

Brenda L. Bass, Professor, Dept of Biochemistry, University of Utah School of Medicine